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This study assessed the level of care burden and its correlates among caregivers of patients with a diagnosis of schizophrenia in Neuropsychiatric Hospital Aro, Abeokuta, Ogun State, South-West Nigeria. The cross-sectional research survey design was used with a sample size of 244, which were randomly selected from the total population of caregivers and spanned over a period of four months. The socio-demographic questionnaire and Zarit Burden Interview (ZBI) were administered for data collection, while the Psychotic Module of MINI-Plus was used to revalidate the diagnosis of schizophrenia. The association between caregivers