EFFECTS OF CHRONIC PROMETHAZINE AND HALOPERIDOL INGESTION ON FEEDING BEHAVIOUR IN MALE ALBINO RATS: SEPARATE AND COMBINED ANALYSIS
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Abstract
Following the concern about gender differences in the effect of haloperidol and promethazine, separately and in combination, on feeding behaviour, as presented by Balogun et al. (2025) with female rats, the present study investigated the same phenomena using male rats this time around. Using 24 male albino rats, divided into four groups of six rats each, Combined drug, haloperidol group, promethazine group and saline group, their feeding behaviour was observed after ingestion of the drugs. It was observed that male rats gained more weight and ate more in all the groups, demonstrating the effect of the drugs on feeding behaviour. The implications of these findings for drug consumption and food intake, especially for those concerned with body weight gain/loss were emphasised and discussed.